***************************************************************** ED50plus v1.0 April 2000 ***************************************************************** ED50plus is a tool for pharmacological analysis. This is a worksheet for MS Excel which allows you to create and analyze dose-response curves. Some of its features are: - Construction of up to 10 curves with up to 30 points each. - Manipulation of X and Y axis (including probit-transformation) - Visualization of each curve. - Calculation of up to 3 intercepts on each curve, thus allowing you to obtain common parameters as ED50, IC50, LD50, PD20, etc. - Averaging of the results, I developed this worksheet in MS Excel 97 (TM). However, this worksheet must also have good performance in any Excel version (4.0 or higher). It is strongly recommended to extensively assess the performance of this worksheet before rely on it. NEITHER I NOR THE INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS ASSUME ANY RESPONSABILITY FOR POTENTIAL ERRORS ON THIS WORKSHEET. This worksheet is FREEWARE, so you can freely distribute it to your colleagues, as long as it is not modified in any way. To distribute this worksheet, please use the compressed file (ED50V10.ZIP), which includes two files: - README.TXT (this file) - ED50V10.XLS (the worksheet) I will deeply appreciate if you send me an E-mail in order to know your opinion about this worksheet. My E-mail is mhvargas@conacyt.mx I intend to develop in the future other worksheets for common statistical or pharmacological procedures. Please, let me know if you are interested in a particular procedure. ----------------------------------------------------------------- Mario H. Vargas, MD Research Unit Instituto Nacional de Enfermedades Respiratorias Tlalpan 4502, CP 14080, Mexico DF, MEXICO. Fax (52-5) 665-4623 E-mail: mhvargas@conacyt.mx -----------------------------------------------------------------