CD24 is reported to be a ligand for P-selectin on human tumor cells.
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CD24lo on memory B cells may represent a separate lineage of B cells. While this issue is quite controversial, the point that memory B cells in mice are low in CD24 has been replicated by several laboratories. Decker et al. and Linton et al. make controversial assignments of CD24lo to a memory lineage. Allman et al. show that CD24hi on splenic B cells mark an immature splenic subset.
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Decker DJ, Linton PJ, Zaharevitz S, Biery M, Gingeras TR and Klinman NR. Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro. Immunity 1995 2:195 PubMed
Allman DM, Ferguson SE, Lentz VM and Cancro MP. Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells. J. Immunol. 1993 151:4431 PubMed
Linton PJ L, Decker DJ and Klinman NR. Primary antibody-forming cells and secondary B cells are generated from separate precursor cell subpopulations. Cell 1989 59:1049 PubMed
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