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PROW: CD158b
[PROW BAR]
PROW and IWHLDA present the GUIDE on:
CD158b
Authors: R. Biassoni; Christina Bottino
Reviewer: Eric O. Long
[GUIDE BAR]

ALTERNATE NAMES FOR CD158b  

MAJOR LINKS FOR CD158b  


FUNCTION
BIOCHEMICAL ACTIVITY OF CD158b   - No information

CELLULAR FUNCTION OF CD158b  

DISEASE RELEVANCE OF CD158b AND FUNCTION OF CD158b IN INTACT ANIMAL   - No information


STRUCTURE
MOLECULAR FAMILY FOR CD158b  

MOLECULAR STRUCTURE OF CD158b  

MOLECULAR MASS OF CD158b  

CELL TYPEMW UNREDUCEDMW REDUCEDComment
NK cells 58 kDa 58 kDa 42 kDa protein core; Inhibiting form (p58.2)
NK cells 50 kDa 50 kDa 36 kDa protein core; Activating form (p50.2)

POST-TRANSCRIPTIONAL MODIFICATION OF CD158b   - No information

POST-TRANSLATIONAL MODIFICATION OF CD158b  


MOLECULAR INTERACTIONS
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF CD158b   - No information

SUBSTRATES FOR CD158b   - No information

ENZYMES WHICH MODIFY CD158b   - No information

LIGANDS FOR CD158b AND MOLECULES ASSOCIATED WITH CD158b  


EXPRESSION
MAIN CELLULAR EXPRESSION OF CD158b  
 
AUTHOR'S ADDITIONAL INSIGHTS ON CD158b  
REAGENTS
CD158b-SPECIFIC MABS NEWLY ASSIGNED AT SIXTH INTERNATIONAL WORKSHOP  
NAME(Workshop IDs)SOURCE or REFERENCECOMMENT
GL183 A Van Aghtoven, Marseille  
CH-L S Ferrini, Genova  

SELECTION OF OTHER CD158b-SPECIFIC REFERENCE MAB   - No information


 
SELECTED REFERENCES ON CD158b  

REVIEWS

1. Moretta A,Bottino C,Vitale M,Pende D,Biassoni R,Mingari MC,Moretta L Receptors for HLA class-I molecules in human natural killer cells. Annu Rev Immunol 1996 14:619 PubMed

2. NK cells, MHC class I antigens and missing self. Immunological Reviews, Vol.155,1997 (Parham, P. ed., whole volume, 19 articles)

PRIMARY CITATIONS

1. Moretta A,Tambussi G,Bottino C,Tripodi G,Merli A,Ciccone E,Pantaleo G,Moretta L A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. J Exp Med 1990 171:695 PubMed

2. Ferrini S,Cambiaggi A,Meazza R,Sforzini S,Marciano S,Mingari MC,Moretta L T cell clones expressing the natural killer cell-related p58 receptor molecule display heterogeneity in phenotypic properties and p58 function. Eur J Immunol 1994 24:2294 PubMed

1. Moretta A,Tambussi G,Bottino C,Tripodi G,Merli A,Ciccone E,Pantaleo G,Moretta L A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. J Exp Med 1990 171:695 PubMed

2. Ferrini S,Cambiaggi A,Meazza R,Sforzini S,Marciano S,Mingari MC,Moretta L T cell clones expressing the natural killer cell-related p58 receptor molecule display heterogeneity in phenotypic properties and p58 function. Eur J Immunol 1994 24:2294 PubMed

WWW RESOURCES


* indicates ammended by reviewer, ** indicates added by reviewer

Portions copyright by Garland Press and by the International Workshops on Human Leukocyte Differentiation Antigens; used with permission

Modified 10/14/99   mpr@mail.nih.gov