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Star Republic: Guide for Biologists

Peptide substrates for kinases

Kinase

Substrate

Akt/Protein Kinase B substrate

Arg-Pro-Arg-Ala-Ala-Thr-Phe

Casein Kinase I Peptide Substrate

Asp-Asp-Asp-Glu-Glu-Ser-Ile-Thr-Arg-Arg  

Casein kinase II

Arg-Arg-Arg-Glu-Glu-Glr-Thr-Glu-Glu-Glu 

cdc2 Protein Kinase Peptide Substrate

Pro-Lys-Thr-Pro-Lys-Lys-Ala-Lys-Lys-Leu 

cGMP-Dependent Protein Kinase (PKG) Peptide Substrate

Arg-Lys-Ile-Ser-Ala-Ser-Glu-Phe 

DNA-Dependent protein kinase

Glu-Pro-Pro-Leu-Ser-Gln-Glu-Ala-Phe-Ala-Asp-Leu-Trp-Lys-Lys

Kemptide (PKA) Peptide Substrate

Leu-Arg-Arg-Ala-Ser-Leu-Gly

MAP kinase substrate

APRTPGGRR

Neurogranin(28-43) PKC Peptide Substrate

Ala-Ala-Lys-Ile-Gln-Ala-Ser-Phe-Arg-Gly-His-Met-Ala-Arg-Lys-Lys  

Protein kinase C

FKKSFKL

Protein kinase C

Arg-Phe-Ala-Arg-Lys-Gly-Ser-Leu-Arg-Gln-Lys-Asn-Val-His-Glu-Val-Lys-Asn

Tyrosine kinase

RRLIEDAEYAARG