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Star Republic: Guide for Biologists

The mouse life cycle

Theiler Stage

days postcoitus (dpc)

Development

1

1

1 Cell

2

1

Beginning of cell division

3

2

Morula

4

3

Advanced division/segmentation

5

4

Blastocyst

6

4.5

implantation

7

5

Formation of egg cylinder

8

6

Differentiation of egg cyliner

9

6.5

Advanced endometrial reaction; prestreak

10

7

Amnion, midstreak

11

7.5

Neural plate, presomite stage; no allantoic bud

12

8

First somites, late head fold

13

8.5

Turning

14

9

Formation and closure anterior neuropore

15

9.5

Formation of posterior neuropore, forelimb bud

16

10

Closure post. neuropore, hindlimb and tail bud)

17

10.5

Deep lens indentation

18

11

Closure lends indentation

19

11.5

Complete separation of lens vesicle

20

12

Earliest sign of fingers

21

13

Anterior footplate indented, marked pinna

22

14

Fingers separate distally

23

15

Toes separate

24

16

Reposition of umbilical hernia

25

17

Fingers and toes joined together

26

18

Long Whiskers

27

19

Newborn mouse

28

19-

Postnatal development

days postpartum (dpp)

1-16

eyelids remain sealed and external ear ducts plugged with periderm

17-

Periderm seals of ears and eyelids vanish; active feeding begins within next 3 days and weaning after 1 week

25-

Entering productive age, sexually mature at 6 weeks for famles and 8 weeks for males.

1 year

Fertility decrease